Now showing items 1-5 of 5

  • Antagonistic coevolution accelerates molecular evolution 

    Paterson, Steve; Vogwill, Tom; Buckling, Angus; Benmayor, Rebecca; Spiers, Andrew J.; Thomson, Nicholas R.; Quail, Mike; Smith, Frances; Walker, Danielle; Libberton, Ben; Fenton, Andrew; Hall, Neil; Brockhurst, Michael A. (Nature Publishing Group, 2010-03-11)
    The Red Queen hypothesis proposes that coevolution of interacting species (such as hosts and parasites) should drive molecular evolution through continual natural selection for adaptation and counter-adaptation. Although ...
  • Bacteriophages limit the existence conditions for conjugative plasmids 

    Harrison, Ellie; Wood, Jamie A.; Dytham, Calvin; Pitchford, Jonathan W.; Truman, Julie; Spiers, Andrew J.; Paterson, Steve; Brockhurst, Michael A. (American Society for Microbiology, 2015-06-02)
    Bacteriophages are a major cause of bacterial mortality and impose strong selection on natural bacterial populations, yet their effects on the dynamics of conjugative plasmids have rarely been tested. We combined experimental ...
  • Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects 

    Hall, James P. J.; Harrison, Ellie; Lilley, Andrew K.; Paterson, Steve; Spiers, Andrew J.; Brockhurst, Michael A. (Wiley, 2015-06-25)
    Plasmids are important mobile elements that can facilitate genetic exchange and local adaptation within microbial communities. We compared the sequences of four co-occurring pQBR-family environmental mercury resistance ...
  • Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum 

    Harrison, Ellie; Guymer, David; Spiers, Andrew J.; Paterson, Steve; Brockhurst, Michael A. (Elsevier, 2015-07-16)
    Plasmids drive genomic diversity in bacteria via horizontal gene transfer [1 and 2]; nevertheless, explaining their survival in bacterial populations is challenging [3]. Theory predicts that irrespective of their net fitness ...
  • Plasmid carriage can limit bacteria–phage coevolution 

    Harrison, Ellie; Truman, Julie; Wright, Rosanna; Spiers, Andrew J.; Paterson, Steve; Brockhurst, Michael A. (The Royal Society, 2015-08-12)
    Coevolution with bacteriophages is a major selective force shaping bacterial populations and communities. A variety of both environmental and genetic factors has been shown to influence the mode and tempo of bacteria–phage ...