Now showing items 1-4 of 4

  • Analysis of the rdd locus in chicken: a model for human retinitis pigmentosa 

    Burt, David W.; Morrice, David R.; Lester, Douglas H.; Robertson, Graeme W.; Mohamed, Moin D.; Simmons, Ian; Downey, Louise M.; Thaung, Caroline; Bridges, Leslie R.; Paton, Ian R.; Gentle, Mike; Smith, Jacqueline; Hocking, Paul M.; Inglehearn, Chris F. (Emory University, 2003-04-30)
    Purpose: To identify the locus responsible for the blind mutation rdd (retinal dysplasia and degeneration) in chickens and to further characterise the rdd phenotype. Methods: The eyes of blind and sighted birds were ...
  • Genetic, ophthalmic, morphometric and histopathological analysis of the Retinopathy Globe Enlarged (rge) chicken 

    Inglehearn, Chris F.; Morrice, David R.; Lester, Douglas H.; Robertson, Graeme W.; Mohamed, Moin D.; Simmons, Ian; Downey, Louise M.; Thaung, Caroline; Bridges, Leslie R.; Paton, Ian R.; Smith, Jacqueline; Petersen-Jones, Simon; Hocking, Paul M.; Burt, David W. (Emory University, 2003-07-01)
    Purpose: To identify the locus responsible for rge (retinopathy globe enlarged) in chickens and further characterise the rge phenotype. Methods: A colony of chickens carrying the rge mutation was rederived from a single ...
  • Mpdz null allele in an avian model of retinal degeneration and mutations in human leber congenital amaurosis and retinitis pigmentosa 

    Ali, Manir; Hocking, Paul M.; McKibbin, Martin; Finnegan, Sorcha; Shires, Mike; Poulter, James A.; Prescott, Katrina; Booth, Adam; Raashid, Yasmin; Jafri, Hussain; Ruddle, Jonathan B.; Mackey, David A.; Jacobson, Samuel G.; Toomes, Carmel; Lester, Douglas H.; Burt, David W.; Curry, William J.; Inglehearn, Chris F. (Association for Research in Vision and Ophthalmology, 2011-09)
    Purpose. To identify the defective gene in the sex-linked, recessively inherited retinal dysplasia and degeneration (rdd) chicken and to search for the human equivalent disease. Methods. Microsatellites from chicken ...
  • Mutation in the guanine nucleotide–binding protein ß-3 causes retinal degeneration and embryonic mortality in chickens 

    Tummala, Hemanth; Ali, Manir; Getty, Paul; Hocking, Paul M.; Burt, David W.; Inglehearn, Chris F.; Lester, Douglas H. (Research in Vision and Opthalmology, 2006-11)
    PURPOSE. To identify the gene defect that causes blindness and the predisposition to embryonic death in the retinopathy globe enlarged (rge) chicken. METHODS. Linkage analysis, with previously uncharacterized microsatellite ...