Browsing by Author "Vlaykova, Tatyana"
Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance Khalil, Hilal S.; Mitev, Vanio; Vlaykova, Tatyana; Cavicchi, Laura; Zhelev, Nikolai Z. (Elsevier, 2015-03-06)Seliciclib (R-Roscovitine) was identified as an inhibitor of CDKs and has undergone drug development and clinical testing as an anticancer agent. In this review, the authors describe the discovery of Seliciclib and give a ...
Vlaykova, Tatyana; Gulubova, Maya; Yovchev, Yovcho; Dimov, Dimo; Vlaykova, Denitsa; Chilingirov, Petjo; Zhelev, Nikolai Z. (InTech - Open Access Publisher, 2012-02)