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Please use this identifier to cite or link to this item: http://hdl.handle.net/10373/489

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Title: Correlation of glutamine synthetase activity with cell magnesium concentration during cell division in yeast synchronized by induction
Authors: Walker, Graeme M.
Thomson, James C.
Slaughter, Colin
Duffus, John H.
Affiliation: University of Abertay Dundee. School of Contemporary Sciences
Keywords: Glutamine synthetase
Cell division
Yeast
Issue Date: 1980
Publisher: Society for General Microbiology.
Type: Journal Article
Refereed: peer-reviewed
Rights: Published version (c)Society for General Microbiology, avalable from doi: 10.1099/00221287-120-2-535
Citation: Walker, G.M., et al. 1980. Correlation of glutamine synthetase activity with cell magnesium concentration during cell division in yeast synchronized by induction. Journal of General Microbiology. 120(2): pp.535-537. [Online] Available from: doi: 10.1099/00221287-120-2-535
Abstract: Synchronization of cell division in the fission yeast Schizosaccharomyces pombe and the budding yeast Kluyveromyces fragilis was achieved by induction using the DNA synthesis inhibitor 2'-deoxyadenosine and by a magnesium-exhaustion technique. The activity of glutamine synthetase in these synchronized cultures oscillated. Variations in the intracellular magnesium concentration were also observed, and peaks in magnesium concentration correlated with peaks in enzyme activity. We suggest that the enzyme from yeast is unstable and that its activity is regulated in vivo by changes in the intracellular concentration of magnesium.
URI: http://hdl.handle.net/10373/489
ISSN: 0022-1287
Appears in Collections:Science Engineering & Technology Collection

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