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Please use this identifier to cite or link to this item: http://hdl.handle.net/10373/695

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Title: Triclosan – an update
Authors: Saleh, S.
Haddadin, R. N. S.
Baillie, S.
Collier, Phillip J.
Affiliation: University of Abertay Dundee. School of Contemporary Sciences
Keywords: Antimicrobials
Mechanism of action
Issue Date: Feb-2011
Publisher: Wiley-Blackwell
Type: Journal Article
Refereed: peer-reviewed
Rights: Published version (c)Wiley-Blackwell, available from http://dx.doi.org/10.1111/j.1472-765X.2010.02976.x. The definitive version is available at www3.interscience.wiley.com
Citation: Saleh, S., et al. 2011. Triclosan – an update. Letters in Applied Microbiology. 52(2): pp.87-95. Available from http://dx.doi.org/10.1111/j.1472-765X.2010.02976.x
Abstract: The discovery in 1998 that triclosan has a site-specific action in the bacterial cell as an inhibitor of NADH- or NADPH-dependent enoyl-acyl carrier protein reductase led to a lively debate in the scientific press. The thesis of this debate was that such a mode of action may allow triclosan to induce resistance and cross-resistance in bacterial cells. The debate last saw review in 2004, and this paper aims at updating our knowledge in this area, given recent research on the topic.
URI: http://hdl.handle.net/10373/695
ISSN: 0266-8254
Appears in Collections:Science Engineering & Technology Collection

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