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Please use this identifier to cite or link to this item: http://hdl.handle.net/10373/922

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Title: Gene transfer in higher animals: theoretical considerations and key concepts
Authors: Smith, Kevin R.
Affiliation: University of Abertay Dundee. School of Contemporary Sciences
Keywords: Gene transfer
Transfection
Gene targeting
Nuclear transfer
Transgenesis
Gene therapy
Issue Date: Oct-2002
Publisher: Elsevier
Type: Journal Article
Refereed: peer-reviewed
Rights: Published version (c)Elsevier, available from http://dx.doi.org/10.1016/S0168-1656(02)00105-0
Citation: Smith, K.R. 2002. Gene transfer in higher animals: theoretical considerations and key concepts. Journal of Biotechnology. 99(1): pp.1-22. Available from http://dx.doi.org/10.1016/S0168-1656(02)00105-0
Abstract: Gene transfer technology provides the ability to genetically manipulate the cells of higher animals. Gene transfer permits both germline and somatic alterations. Such genetic manipulation is the basis for animal transgenesis goals and gene therapy attempts. Improvements in gene transfer are required in terms of transgene design to permit gene targeting, and in terms of transfection approaches to allow improved transgene uptake efficiencies.
URI: http://hdl.handle.net/10373/922
ISSN: 0168-1656
Appears in Collections:Science Engineering & Technology Collection

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